… hypothesis, proof of concept and possible cure for multiple sclerosis (MS) in 2009, 1 e3
many were intrigued by the simplicity of the ‘chronic cerebrospinal venous insufficiency’(CCSVI) …

… findings and doubt the blinded assessment of the reported … We believe that we did not
need to specify how blinding of … in the CCSVI-MS study was performed fully blinded, as are all …

… CCSVI hypothesis, this result opposes a key issue of the hypothesis. … CCSVI pattern prevailed
in several blinded trials, leaving interestled investigation, supported by insufficient blinding…

… that CCSVI is a consequence of MS or of aging. Blinding of sonographers is a key point in
studying CCSVI … a cross-sectional blinded study to evaluate the association of CCSVI with MS, …

… copper homeostasis was suggested to be a key factor in early neuropathological events in
… not meet minimum requirements of scientific accuracy (blinding, sham-operation and control …

… the endovascular treatment of CCSVI in MS patients outside … CCSVI and MS completely
justifies performance of blinded, … assessors, and/or blinded MR measures. The latter are not …

… the lack of consensus around a number of key issues including diagnostic techniques,
whether there is in fact a meaningful association between CCSVI and MS and, if so, what the …

… But then in the next breath told me that I’d be blind in a … the same thing that I’d be blind
in a wheelchair. And I never … not done so, our key informants also corroborated that they …

… of the individual CCSVI criteria and the CCSVI diagnosis on … model that can study such
relationships will be the key factor … between CCSVI and MS justifies performance of blinded, …

… for the presence of CCSVI in comparison with normal controls and patients with other
neurological diseases. Studies should be blind and the assessment of CCSVI should be performed …